Emerald BioStructures announces discovery of small molecule modulators of PDE4 (EurekAlert!)

( MacDougall Biomedical Communications, Inc. ) Emerald BioStructures announced today a publication in the Dec. 27, 2009, advance online issue of Nature Biotechnology, detailing the application of structure-based drug design to engineer new allosteric small molecule modulators of the enzyme phosphodiesterase-4 (PDE4), with reduced side effects. According to the paper, the researchers established …

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Emerald BioStructures announces discovery of small molecule modulators of PDE4 (EurekAlert!)